oral administration of glutathione: bioavailability in rat pancreas Enhancing the Glutathione Using Innovative Analogue Approaches Frontiers | The role of

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doi: 10.1016/j.brainres.2010.09.021 137 BasuSKPradhanSdu PlessisAJBen-AriYLimperopoulosC

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However, 5-HIAA exhibited mild protective activity, achieving less than 50% protection from erastin toxicity (Fig

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Significantly increased levels of superoxide dismutase (SOD), glutathione (GSH), glutathione peroxidase (GPx), and SOD2 protein expression, while significantly reducing levels of malondialdehyde (MDA) and lactate dehydrogenase (LDH) in peri-infarct brain tissue.\nSignificantly increased optic atrophy 1 (Opa1) protein expression without altering levels of Fis1, Drp1, MFN1, MFN2.\nSignificantly increased CK2 protein levels and AKT phosphorylation (p-AKT/AKT ratio) in peri-infarct brain tissue