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Description
During hypoxia, oxygen sensing and signal transduction are largely governed by prolyl hydroxylase domain proteins (PHD1/2/3), which hydroxylate target proteins in an oxygen-dependent manner 8,9
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Novel PTEN mutations in patients with Cowden disease: absence of clear genotype-phenotype correlations
This may involve a combination of nutritional therapy, hormone balancing, targeted supplements, and other natural healing techniques
10.1016/j.cell.2023.01.002
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