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Copper has been shown to influence the aggregation pathway of A, modulating its assembly, making it more toxic, and participating in the generation of ROS involved in oxidative stress, a key event in AD pathogenesis (Esmieu et al., 2019)

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de L., Lima, R

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The amylin signaling pathway is distinct from and complementary to GLP-1 receptor signaling, as amylin primarily influences hedonic appetite pathways (reward-driven eating) while GLP-1 primarily affects homeostatic appetite regulation
Toxicology 442, 152526