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50 OhtaK.OhigashiM.NaganawaA.IkedaH.SakaiM.NishikawaJ.et al (2007)

This leads to a condition called oxidative stress

Glutathione Conjugation in Xenobiotic Metabolism and in the Production of Intrinsic Bioactive Compounds The conjugation of xenobiotics with GSH is catalyzed by glutathione S-transferase (GST), and, along with glucuronidation and sulfation, this process constitutes a major detoxification system in the liver and kidney [12,18]

The Tf/TfR1/DMT1 pathway is a key iron transport mechanism through the BCSFB

Dosages used ranged from 1200 to 3000 mg per day for 4 weeks to 14 months, or from 2400 to 3600 mg for short-term use (34 days)
GSH-dependent photolabeling of multidrug resistance protein MRP1 (ABCC1) by [125I]LY475776
