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Although calcitriol is a major hormone involved in, primarily, calcium and phosphorous homeostasis, the VDR is found widely distributed in numerous different cells throughout the body

Growth hormone is also produced by lymphoid organs, such as the thymus, the spleen, and immune cells

Many other inhibitors/agonists may also be used

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10.3390/cancers13153752 15 MahmoudiM.HofmannH.Rothen-RutishauserB.Petri-FinkA

Therefore, it is not surprising that dramatically greater global tyrosine phosphorylation is seen in PMA-stimulated Gsr / neutrophils than in yeast- or PMA-treated macrophages (Fig