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De plus, la rtention de la vitamine B12 diminue au fur et mesure de la restauration des rserves

[1] A common starting regimen in adults with normal renal and hepatic function is 1 mL intramuscularly once or twice weekly, titrated every four weeks according to biochemical markers such as fasting lipid panel, liver transaminases, and serum carnitine

It does not constitute clinical evidence of efficacy in humans

Valentino, M A et al

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This ratio provides a manageable volume of liquid that is not too large for a single injection site