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Antioxidant defense systems can be broadly categorized into four types: preventive antioxidants, radical scavenging antioxidants, repair antioxidant systems, and cellular signalling antioxidant defense systems

Yoo Du-yeol , we approach such topics with both scientific rigor and a practical clinical perspective

Insights into porphyrin chemistry provided by the microperoxidases, the haempeptides derived from cytochrome c

Several GSTP1 inhibitors are currently in preclinical development, and our findings suggest that their antineoplastic activity may be potentiated through concurrent disruption of PHD2

This bacterium is unable to synthesize endogenous GSH as a cofactor for this enzyme but acquires GSH from host tissues via the GshT transporter

In theory, targeting any node of cysteine-GSH-GPx4 axis seems to be sufficient to induce ferroptosis
