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Controlling the role of BPC 157 likely involves its particular interaction with the major systems involved in wound healing, such as the NO-system (counteracted harmful events, arising from either NO-blockade or NOS-substrate application) (Sikiric et al., 2014) and the prostaglandins system (i.e., large extent of the counteracted NSAIDs toxicity (Sikiric et al., 2013) as well as counteracted developing and already formed adjuvant arthritis in rats (Sikiric et al., 1997c))

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doi: 10.1111/jnc.15144 46 De StefanoN.GiorgioA.BattagliniM.RovarisM.SormaniM

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This suggests that GHK-Cu and related peptides could be investigated as potential non-addictive research alternatives in the context of pain management, alongside opiate medications and NSAIDs, which are known for their potential side effects, including negative impacts on cardiovascular health

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