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however, this pathway is reported to be inactive in most tissues, and in the few tissues in which it is active, its activity is reduced in tumors from the corresponding tissue 27

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V., Toyokuni, S., Woerpel, K

For Research Use Only Not intended for human consumption or therapeutic use

The main limitation of this study is that it lacks a detailed estimate (by cardiac MRI) of the final infarct size compared to the initial area at risk to further reinforce these findings and provide a better comparison with animal data

For instance, miR-145-5p has been implicated in RGC apoptosis via the PI3K/AKT signaling pathway, highlighting the potential of modulating microRNA expression as a neuroprotective strategy (115)