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Phase 1: Retatrutide foundation (weeks 1-8) During this initial phase, the goal is to establish retatrutide tolerance before adding cagrilintide

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Methodology This manuscript was designed as a narrative and integrative review rather than a systematic review, with the aim of synthesizing and critically interpreting the most relevant and mechanistically informative evidence on menstrual cycle physiology and nutrient metabolism

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Its blended format helps reduce the need for separate vial handling and may support more efficient preparation in laboratory protocols