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Abstract Castration-resistant prostate cancer demonstrates intrinsic or acquired resistance to second-generation androgen-targeted therapies, posing a challenge in clinical treatment

However, PAR-1 mediates activation of platelets by thrombin neither in mouse nor in human

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J Neurochem 104:113123 Czeredys M, Mysiorek C, Kulikova N, Samluk L, Berezowski V, Cecchelli R, Nalecz KA (2008) A polarized localization of amino acid/carnitine transporter B(0,+) (ATB(0,+)) in the bloodbrain barrier

These findings appear to be a result of disease and not other variables such as age or biological sex, as no significant difference in biological sex distribution within the cohort was found (Students t Test, p = 0.98) (Supplementary Data 1)

Peptides are short chains of amino acids that act as biological signals, telling specific cells or hormones to activate, increase production, or change behavior