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The genotype of an individual does not explain the dynamic process impacted by several environmental and/or disease-related factors, however, the metabotype serves as the culmination of the genome-environment-microbiome interplay (Figure 3)

Int J Mol Sci 23(19):11740 Pohanka M (2013) Role of oxidative stress in infectious diseases

Regulation of DJ-1 by glutaredoxin 1 in vivo: implications for Parkinsons disease

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Actinic cheilitis: Damage caused by years of sun exposure
