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Both GH receptors and IGF-1 receptors are expressed throughout the brain, and preclinical studies document roles for these signals in neurogenesis, synaptic plasticity, and neuronal survival

For both NmlR and AdhR, no evidence of S -alkylation by formaldehyde, formaldehyde generators, or downstream formaldehyde detoxification products has been reported thus far

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Although the importance of mitochondria in the development and function of the nervous system is widely accepted, further studies are required to understand how the mitochondrial networks contribute to dendritogenesis, cell fate, connectivity, and plasticity

Counteracting these modifications is the mitochondrial protease Lon, which degrades ROS-modified mitochondrial proteins 106

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