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The authors also conducted experiments to exclude the possibility of LPX-1 inhibiting NETosis and affecting IgG or IFN- production [27]

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Iron deficiency per se and iron deficiency-induced hypoxia can trigger the activation of HIFs, which are known to mediate cancer progression by upregulating target genes associated with angiogenesis and the metabolic reprogramming of tumor cells (106, 107), thus causing resistance to chemo- and radiotherapies (108, 109)

Decreases muscle damage by protecting the integrity of the muscle tissue, preserving the contractible function