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A mismatch can develop between the haptocorrin-bound pool, which makes up most of the total, and the smaller active fraction on transcobalamin that cells depend on

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10.1016/j.cell.2013.11.037 [DOI] [PMC free article] [PubMed] [Google Scholar] 5.Camacho-Pereira J, Tarrago MG, Chini CCS, Nin V, Escande C, Warner GM, et al

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increased H1N1-specific immunoglobulin A responses in the plasma and colostrum of mothers, but not in babies