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reported that GPX3 protein levels in ALS model rats carrying the mutant superoxide dismutase-1 (SOD1) H46R initially increased during the pre-symptomatic stage but decreased as the disease progressed [187]

Abdalla, Repurposing benzimidazole and benzothiazole derivatives as potential inhibitors of SARS-CoV-2: DFT, QSAR, molecular docking, molecular dynamics simulation, and in-silico pharmacokinetic and toxicity studies, J

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Consistently, quantification at the SC- stage showed that FGB levels reached nearly 14% in GPX2 KO cells compared to only ~1% in WT, and AFP protein levels were also significantly increased in KO cells relative to WT counterparts (Supplementary Fig