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Ultimately, integrating dynamic biomarkers, multi-omics, and artificial intelligence to tailor treatments to individual patient profiles holds the key to finally fulfilling the promise of effectively managing MIRI

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Furthermore, zincmethionine, selenium (SelPlex), thiamethoxam, clothianidin, and imidacloprid insecticides altered flight muscle activity and heat balance, which may indirectly affect energy expenditure and resource intake, highlighting the significance of body weight as an additional sensitive indicator of stress in honeybees [15, 28]

If the absorbed drug is a P-gp substrate, the drug is actively released back into the intestinal lumen

Future studies should focus on the metatranscriptome of the gut to better assess the microbial contribution to GR conversion

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