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Each freeze-thaw cycle subjects the peptide to ice crystal formation, which mechanically disrupts molecular structure and concentrates solutes as water freezes

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This is why we identify the result as chromatographic purity by HPLC rather than simply listing purity. We believe researchers should understand exactly what is being measured and how that result should be interpreted

May 15 2017;132:1-8

This normalization can result in improved sleep quality, mood stabilization, and enhanced cognitive function Anisimov et al., Neuroendocrinol Lett , 2001