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The majority found no difference in 25(OH)D concentrations in comparison to either pre-treatment concentrations or to a control group 111113, 116, 117, 119

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Moreover, IGF-IR phosphorylation is elevated in breast cancer cells resistant to the p110 isoform-selective inhibitor BYL719, making the BYL719-resistant cells sensitive to IGF-IR inhibition [126]
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Human hepatocellular carcinoma tumor-derived endothelial cells manifest increased angiogenesis capability and drug resistance compared with normal endothelial cells

Use the clinical schedules as a framework, not a rigid rulebook

Bouard D, Alazard-Dany N, Cosset FL