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The GOx activity assay of ZFG NPs (a) The cascaded catalytic effect verifies the generation of H 2 O 2

N Engl J Med 382(20):19261932

The authors also stated that the pattern of cellular and protein findings suggests that the brain's own immune system (not immune abnormalities from outside the brain) and the neuroinflammatory process appears to be an ongoing and chronic mechanism of central nervous system (CNS) dysfunction

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Alterations in the gut microbiota throughout this time precipitate the onset of chronic disorders such as asthma, allergies, and obesity in both adulthood and childhood (505, 506)

Hypothesis: pentoxifylline is a potential cytokine modulator therapeutic in COVID-19 patients