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Physicians may prescribe compounded medications as needed to meet patient requirements or address drug shortages

In addition, the age-related decrease in the expression of SIRT1 and PGC-1 in cochlear tissue is observed in C57BL/6 mice, and the overexpression of SIRT1 suppressed apoptosis and promoted cell proliferation in HEI-OC1 cells 78

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mPTP, mitochondrial permeability transition pore
