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This single event triggers three major downstream signaling pathways that collectively govern neuronal health: the MAPK/ERK pathway, the PI3K/Akt pathway, and the PLCgamma pathway

PD patients have been found with reduced total NM volume indicated by NM-MRI (Mueller et al., 2014

When this system becomes disrupted, patients may experience symptoms such as abdominal pain, bloating, diarrhea, constipation, urgency, food sensitivity patterns, fatigue, or systemic inflammatory complaints
Yang ES, Richter C, Chun JS, Huh TL, Kang SS, Park JW

[DOI] [PubMed] [Google Scholar] 620.Benatar, M

Molecular basis of retinal remodeling in a zebrafish model of retinitis pigmentosa
