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Frijhoff J, Winyard PG, Zarkovic N, Davies SS, Stocker R, Cheng D et al (2015) Clinical relevance of biomarkers of oxidative stress

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In addition, testosterone administration has been associated with worsening of sleep-disordered breathing and obstructive sleep apnoea in susceptible individuals, thereby compounding cardiovascular strain and arrhythmic risk (85)

It is a natural compound that can be synthesized in the body from essential amino acids lysine and methionine or obtained through the diet, primarily stored in skeletal muscles

Hazen, M.D., Ph.D., senior author of the study and section head of Preventive Cardiology & Rehabilitation at the Cleveland Clinic