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This study analyzed the clinical traits of hepatobiliary adverse event reports related to triazole antifungal agents, conducted a detailed comparative analysis of PT, and identified 11 novel PTs not mentioned in the drug labeling, such as vanishing bile duct syndrome, steatohepatitis, and hepatolysis

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Results Constitutive System xc- deficiency led to an approximately threefold decrease in glutathione levels in the pancreatic islets as well as cystine shortage characterised by upregulation of Chac1

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