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The primary mechanism of metformin involves the activation of AMPK, enhancing cellular energy homeostasis and metabolic function

In this work, we also listed two enzymes that are related to the persistent phase of Mtb , Isocitrate lyases (ICL1 and ICL2) and Lysine- aminotransferase (LAT)

A.Jr.VanucchiH.et al (2009)

Weeks 1-2: Shedding slows dramatically
Aapro MS, Bohlius J, Cameron DA, et al

Crystal structure of L,Dtranspeptidase LdtMt2 in complex with meropenem reveals the mechanism of carbapenem against Mycobacterium tuberculosis