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The confirmation of oxidative stress as one of the pathological signatures of FRDA led to the search for antioxidants which can be used as therapeutic modality

[DOI] [PubMed] [Google Scholar] Ruggenenti P., Cattaneo D., Loriga G., Ledda F., Motterlini N., Gherardi G., Orisio S., Remuzzi G

However, an important factor for miRNA-mediated translational repression- GW182 has not been detected in any studies (Ro et al., 2013

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Because both factors vary widely between individuals, predicting who will be affected is imprecise without specific testing

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