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The synergy case: why the best formulas contain both Research published in the Journal of Clinical and Aesthetic Dermatology found that vitamin C helps convert oxidised glutathione back to its active form

Chapter 17, pp 342366

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PKC-CREB-Nrf2 signalling induces HO-1 in the vascular endothelium and enhances resistance to inflammation and apoptosis

doi: 10.3389/fimmu.2025.1669246 Received 19 July 2025 Accepted 28 August 2025 Published 12 September 2025 Volume 16 - 2025 Edited by Guan-Jun Yang, Ningbo University, China Reviewed by Suman Biswas, West Bengal University of Animal and Fishery Sciences, India Amany Ramah, University of Miyazaki, Japan Adela Mora-Gutierrez, Prairie View A&M University, United States Gumercindo Franco, Federal University of Mato Grosso do Sul, Brazil Updates Copyright 2025 Somagond, Das, Dang, Yadav, Kittur, Panda, Devi, Kamboj and Alhussien

The two major factors that can affect DNA methylation include genes (non-modifiable) and the environment (modifiable), of which diet is a key factor