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Description
Dendritic spine loss in the hippocampus of young PDAPP and Tg2576 mice and its prevention by the ApoE2 genotype
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Trimethylamine-N-oxide is an intestinal microbe-dependent metabolite that binds to the farnesol X receptor (FXR), inhibiting the FXR-FGF15 axis and activating the Wnt/-catenin signaling pathway (Zhang et al., 2024)

Effects of tricyclic antidepressants on platelet monoamine oxidase activity
The proposed purpose is to help protect glutathione during digestion and facilitate delivery across biological membranes

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