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Crohns Colitis 17 , 767776 (2023)

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For more information, please view the ICF below: REASON: Study to Evaluate Transmural Healing and Disease Modifying Effect of Guselkumab in Crohns Disease Patients The REASON study is a Phase 3b, open-label, multicenter clinical trial sponsored by Janssen evaluating TREMFYA (guselkumab) in adults with Crohns disease

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Additionally, GLP-1RAs increased the expression levels of genes involved in cholesterol uptake, such as LDLR , scavenger receptor class B type I gene ( SR-B1