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Disulfidptosis is a regulatory form of cell death induced by disulfide stress (Liu et al., 2023a), which is caused by an imbalance of the intracellular glutathione and thioredoxin antioxidant systems, leading to the accumulation of disulfide bonds

Metabolic Dynamics in Astrocytes and Microglia During Post-Natal Development and Their Implications for Autism Spectrum Disorders

This pattern mirrors how regulators like NAD are tracked across aging, mapping core metabolic players in detail long before they become medicines

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In summary, an improved understanding of the ferroptosis mechanism and the role of ferroptosis in CCH will create new opportunities for VCI diagnosis and therapeutic intervention

Gekov A, Petivalsk M