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RoeNDXuXKandadiMRHuNPangJWeiser-EvansMCet alTargeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy

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As a clinician, my role is to educate all patients about their bodies so that they can make an educated decision about their treatment. Hannah Zetterstrand-Robinsons interests revolve around orthopedics, her medical specialty

Under physiological conditions, Nrf2 remains sequestered in the cytoplasm by its inhibitor, the Kelch-like ETC-associated protein 1 (Keap1), but oxidative or electrophilic stress triggers Nrf2 dissociation, nuclear translocation, and binding to antioxidant response elements (AREs), upregulating genes such as heme oxygenase-1 (HO-1), NAD(P)H quinone oxidoreductase 1 (NQO1), and glutathione S-transferases (GSTs) (Cuadrado et al., 2019)