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Perhaps, not surprisingly, their protective efficacy is often lost in murine models where the gene encoding Nrf2 has been disrupted
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doi: 10.1016/j.jhep.2013.12.025 168 WangCMaCGongLGuoYFuKZhangYet al
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Interestingly, these often precede the onset of motor symptoms and are increasingly considered prodromal markers of the disease [5]
