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81,143,144,145 Even though the overexpression of enzymes involved in both the synthesis and breakdown of H 2 S has thus far only been reported for colorectal cancer, 134 it can be envisaged that overexpression of both enzymatic pathways might be a common trait for any cancer type where H 2 S production is increased, as excess H 2 S can become toxic even for the most robust cancer cells (see below)

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Sulforaphane protects against 6-hydroxydopamine-induced cytotoxicity by increasing expression of heme oxygenase-1 in a PI3K/Akt-dependent manner

Retrieved from Caporuscio, J