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Glutathione S-transferases (GST) are an important group of enzymes that catalyze the nucleophilic addition of GSH to electrophiles

(2021) identified the first potent human SQOR inhibitor, with an IC 50 of 29 nM

Efficacious fluorescence turn-on probe for high-contrast imaging of human cells overexpressing quinone reductase activity

Indirect mechanisms include the modification of host-derived compounds that then modulate host metabolic processes

BMC Genomics 17, 260

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