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Another study found that after six days of treatment of valproic acid with a dosage of 300 mg/kg, there was a reduction in angiotensin II and a reduction in HDAC1 expression in a high-fat-diet rat model (Choi et al., 2017)

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Additionally, stored glycogen can contribute to prolonged exercise duration, improving endurance, performance, and fat loss

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Interestingly, it has been found that this syndrome can also be caused by a mutation in the mitochondrial ribosomal protein MRPS22 with deficiencies of OXPHOS complexes I, III, and IV in fibroblast mitochondria [392]