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doi: 10.1016/j.mce.2017.08.016 34 NaidanNRivaadOEMuukhaiNJanlavM
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Limitations of ASOs include rapid degradation and inability to cross the bloodbrain barrier, requiring treatment with repeated intrathecal injections [205]
No penetration of orally administered N-acetylcysteine into bronchoalveolar lavage fluid
These issues are more common when consuming doses of around 500 mg daily over a period of 60 to 90 days
Cellular Signalling, 23 , 19271935
