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Similar endogenous formation of AGE and cellular self-damage has also been observed in other types of cells, including hepatocytes, cardiomyocytes, and skeletal muscle cells [19]

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3.1 The aging defect 3.1.1 Heart under standard and ischemic conditions The mitochondrial defects in the aging heart are localised specifically in the interfibrillar mitochondrial (IFM) population [15], which is located between the myofibrils [27]

Huang M, Lucas K
