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The cells were then distributed across cell culture plates and grown at 37C, 5% CO 2 for the duration of the experiment

Several bacteria, including Salmonella enterica , Roseburia inulinivorans and representatives of Lactobacillus , Ruminococcus obeum and Bacteroides thetaiotaomicron , can synthesize 1,2-propanediol from various carbon sources such as deoxy sugars (e.g., fucose and rhamnose), dihydroxyacetone or lactic acid [122,206,207]

Conservative approaches include periodic breaks from protocols, regular health monitoring, and avoiding aggressive dosing

S.CamposL

Thus, developing novel iron chelators, particularly nanoscale formulations, may represent a future direction to reduce side effects while maintaining or enhancing therapeutic efficacy (Kalanaky et al., 2016)