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doi: 10.1093/jn/126.11.2873

In fact, FMO1 is also participated in the oxidization of TMA to TMAO, however, its specific activity is only 1/10 that of FMO3 ( Numerous studies indicate that inhibition of FMOs, especially FMO3, is an effective target for reducing TMAO concentrations (Zhu et al., 2018

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2 Factors such as aging, dyslipidemia, high blood pressure, diabetes, obesity, unhealthy diet, lack of exercise, and smoking help initiate atherosclerosis by promoting endothelial dysfunction, oxidative stress, and inflammatory pathways

[DOI] [PMC free article] [PubMed] [Google Scholar] 176.Zhao L., Liu S., Xu J., Li W., Duan G., Wang H., Yang H., Yang Z., Zhou R

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