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Am J Physiol Lung Cell Mol Physiol 312(5):L722L730
Santomasso, B
High-pressure homogenization is commonly used to prepare such nanosuspensions, significantly improving dissolution rates [219]
It is our hypothesis that in the setting of COVID-19 and oxidative stress, patients with comorbidities may have compromised levels of GS and GCL, the enzymes involved in GSH synthesis For this reason, we suggest directly supplementing liposomal glutathione, instead of NAC as patients with deficient levels of GS and GCL will not be able to use NAC as substrate for GSH synthesis
The logistical advantage of this stack is that 5-Amino-1MQ doesnt require cold-chain handling, reducing storage complexity when running concurrent protocols
In contrast to the studies of Moylan et al
