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Experimental methods for evaluating these markers including immunohistochemistry staining for DNA damage markers histone variant H2A histone family member X (H2AX), P53-binding protein 1 (53BP1), and promyelocytic leukemia (PML), the loss of nuclear protein lamin B1, intracellular absence of high mobility group box 1 (HMGB1) and bulk RNA-seq profiling for SASP factors

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Research has shown that alpha msh peptids have significant antibacterial effects against pathogens such as Staphylococcus aureus and Candida albicans

Structural insights of AKT and its activation mechanism for drug development