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However, allosteric modulators, both positive and negative, may offer superior efficacy with less danger of downregulation

Quantitative proteomics identifies ncoa4 as the cargo receptor mediating ferritinophagy

Interestingly, KEAP1 is the third most frequently mutated gene in lung adenocarcinoma (LUAD) and often co-occurs with oncogenic mutations in KRAS (Cancer Genome Atlas Research Network, 2014)

(Neelakantan et al., 2018)

Proteomic profiling in blood plasma was performed by the UKB Pharma Proteomics Project using the antibody-based Olink Explore 3072 proximity extension assay, which measured 2941 protein analytes across eight panels and captured 2923 unique proteins 41
& Zarghami, N
