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CrossRef Global patterns of breast cancer incidence and mortality: A populationbased cancer registry data analysis from 2000 to 2020 Shaoyuan Lei, Rongshou Zheng, Siwei Zhang, Shaoming Wang, Ru Chen, Kexin Sun, Hongmei Zeng, Jiachen Zhou, Wenqiang Wei Cancer Communications.2021

The rationale is straightforward: a 120kg individual has significantly more tissue volume for the peptide to distribute through than a 70kg individual, which affects both the effective concentration at receptor sites and the perceived intensity of side effects

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422 Topical administration of the TLR7 agonist imiquimod was shown to increase antigen-bearing cDC2 populations, resulting in partial restoration of vaccination efficacy through targeted phenotypic restoration
