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Enzymatic dopamine peroxidation in substantia nigra of human brain

AGXT (Alanine-Glyoxylate Aminotransferase): Mutations in this gene can contribute to primary hyperoxaluria, a condition where oxalates accumulate excessively in the body

100 mM H 2 O 2 stock solutions were used for analysis

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Interestingly, Na + is needed also in the intraliposomal compartment (intracellular side) but, at a concentration much lower than the external one, corresponding to the physiological intracellular Na + concentration

doi: 10.1038/nrdp.2017.11