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W.LiuA.JainR.San MiguelM.et al

The abnormal extracellular matrix and tumor vasculature surrounding tumor cells result in uneven drug distribution within the tumor, thereby reducing the effective drug concentration ( CAFs play a critical role in tumor progression and drug resistance by secreting growth factors and cytokines that promote tumor cell proliferation and migration

& Portman, O

The cells not treated with H2O2 were collected at similar time-points

Cpr: Supernatant protein concentration, mg/mL

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