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Description
The progression of this research is anticipated to catalyze the evolution of a new cadre of auricular therapeutics, designed to mitigate the risks of intracochlear toxicity engendered by aminoglycoside antibiotics, thereby enhancing the global patient populace's quality of life and offering a constellation of targeted compounds that will inform the architecture of next-generation cochlear protective devices
[DOI] [PubMed] [Google Scholar] 94.Nadeem A., Siddiqui N., Alharbi N.O., Alharbi M.M., Imam F., Sayed-Ahmed M.M
Free Radical Biol Med (2010) 49(11):160316

-GT is only located extracellularly [36], and ICGS and ICYS did not appear to be transported back into the cells, most likely due to the absence of the organic anion transporters (OAT1 and OAT3) in the parent ciPTEC used in this study [37]

They are a dynamic equilibrium process catalyzed by an enzyme called glutathione reductase (GR)
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