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The enigma of the pathogenesis of the Jarisch-Herxheimer reaction

Release 173, 7588

Grune and Stratton, Orlando, pp 7476 Schneider WC 1957 Determination of nucleic acids in tissues by pentose analysis

doi: 10.1016/j.molcel.2021.08.027

And these protein gradually degrades formaldehyde into carbon dioxide

2.3 Cisplatin induces mitochondrial dysfunction When cisplatin enters the mitochondria, it acts directly on the inner mitochondrial membrane, leading to the impairment of the function of the electron transport chain, the reduction of ATP production and the induction of ROS generation (Elmorsy et al., 2024), and the inhibition of the efficient antioxidant defence system composed of glutathione (GSH) and enzymes, such as superoxide dismutase (SOD) and glutathione peroxidase (GPx), in the interstitial space of the mitochondrial membrane