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NOTCH1 mutations in +12 chronic lymphocytic leukemia (CLL) confer an unfavorable prognosis, induce a distinctive transcriptional profiling and refine the intermediate prognosis of +12 CLL

Science (2019) 363(6428):74853

In breast cancer, RNF5 loss is associated with increased ASCT2 expression, finally leading to poor patient outcomes, and poor response to paclitaxel (Ma et al., 2021), colon cancer (Ma et al., 2018), pancreatic cancer (Wang et al., 2022), and TNBC (Van Geldermalsen et al., 2016)

[PubMed 6496516] 820

Unfortunately, the studies investigating the differential, temporal expression of EAATs in NP models were mostly conducted in male rodents, so the relationship between EAAT expression, the induction and maintenance of NP, and sex differences, are not well understood

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