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An increasing body of literature has shown that intercellular mitochondrial transfer occurs naturally between cells and involves several distinct mechanisms, including tunneling nanotubes, extracellular vesicles, and the release of free mitochondria (reviewed in [28])

Metformin use and cognitive function in older adults with type 2 diabetes following a Mediterranean diet intervention

Current Opinion in Cell Biology

European Journal of Neurology, 27, 19181929

10.1371/journal.pone.0218490 138 WangQ.-S.WangY.-L.ZhangW.-Y.LiK.-D.LuoX.-F.CuiY.-L

The results obtained suggest that NO participates, at least in part, in the gastroprotective effect of (-)-Carveol since, in the presence of the inhibitor L-NAME, its effect was partially reduced