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Additionally, the combination data were re-evaluated using an additive model, positing that drug-related hazards may amplify the potential risk, with the relevant formulas provided in Supplementary Tables S4,S5 ( Results Signal and risk factor analysis of monotherapy for 10 AEDs The current investigation examined the reporting rate of HE reporting among patients receiving treatment with ten AEDs as recorded in FAERS from the first quarter of 2013 to the third quarter of 2024

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Rules for sedative (soporific) ingredients (table 2.2) If sedative ingredients (table 2.2) are combined, the sum of the percentages of the maximum daily reference dose must not exceed 120%, for all sedative ingredients in the product (including sedative ingredients supported by other NNHPD monographs such as melatonin)